Catherine B. Kunst
Research Professor, Eleanor Roosevelt Institute
Address and Phone Numbers:
Eleanor Roosevelt Insitute
University of Denver
2101 E. Wesley Avenue
Denver, Colorado 80208
Office: (303) 871-5658
Room 203
E-mail: ckunst@du.edu
Research Interests:
Amyotrophic Lateral Sclerosis "Lou Gehrig's Disease"
Dr. Kunst's research focuses on ALS (amyotrophic lateral sclerosis or Lou Gehrig's Disease), a fatal neurodegenerative disease characterized by progressive paralysis. Dr. Kunst discovered that certain genetic variations in the mouse that can prevent ALS in mice otherwise destined to die from the disease. She is currently working to identify these protective genes and what they do in the hope that this discovery will lead to medicines that mimic the effect of the protective genes for treating ALS in people.
Degrees and Education:
- 1994 Ph.D., Biochemistry & Molecular Biology
Emory University - Atlanta, GA
- 1988 B.S., Biochemistry
Case Institute of Technology - Cleveland, OH
Professional Experience:
- 2005 - Present
Interim Director
Eleanor Roosevelt Institute
University of Denver
- 2003 - Present
Assistant Research Professor
Eleanor Roosevelt Institute
University of Denver
- 1998 - 2003
Scientist
Eleanor Roosevelt Institute
Recent Publications:
(Abstracts of some articles are available)
- Kunst C (2004) Complex genetics of amyotrophic lateral sclerosis. Am J Hum Genet. 75(6):933-947
- Kunst C, Messer L, Gordon J, Haines J, Patterson D (2000) Genetic mapping of a mouse modifier gene that can prevent ALS onset. Genomics 70:181-189
(DOI: 10.1006/geno.2000.6379)
- Schmidt PJ, Kunst C, Culotta VC (2000) Copper Activation of Superoxide Dismutase 1 (SOD1) in Vivo: ROLE FOR PROTEIN-PROTEIN INTERACTIONS WITH THE COPPER CHAPERONE FOR SOD1. J. Biol. Chem. 275(43): 33771-33776.
(DOI: doi:10.1074/jbc.M006254200)
- Kunst CB, Mezey E, Brownstein MJ, Patterson D (1997) Mutations in SOD1 associated with amyotrophic lateral sclerosis cause novel protein interactions. Nat Genet. 15(1):91-4.
(DOI: 10.1038/ng0197-91)
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